01 A blood-spatter analyst who moonlights as a serial killer with a strict moral code.
15 Best Hollywood TV Series of the 2000s
By Vlad Zakh · January 14, 2026
The Sopranos and The Wire arrived within a few years of each other and effectively invented the prestige-drama conversation. Mad Men and The Office prove the decade wasn’t only grim antihero dramas.
01 
02 A suburban widow turned marijuana dealer trying to keep her family afloat.
03 A structural engineer getting himself imprisoned to break his brother out.
04 A breezy look at a young star's inner circle navigating fame in Hollywood.
05 A dense, joke-packed family comedy that rewards rewatching more than almost any sitcom made.
06 A grim, politically sharp sci-fi reboot about the last survivors of humanity.
07 A profane, poetic look at a lawless gold-rush town becoming a real place.
08 A real-time counterterrorism thriller that reshaped how action shows were structured.
09 A small-town Texas football drama with far more heart than its premise suggests.
10 A mockumentary sitcom about a mundane paper company that became one of the most beloved comedies ever.
11 A moody, meticulous look at a 1960s Madison Avenue ad agency and the man at its center.
12 A chemistry teacher turned meth kingpin, in one of the most acclaimed character arcs ever filmed.
13 A plane crash on a mysterious island that turned into one of the decade's biggest pop-culture obsessions.
14 A sprawling, novelistic look at Baltimore through police, drug dealers, docks, schools, and City Hall.
15 Widely credited with launching the prestige-TV era, following a New Jersey mob boss in therapy.